Mast Cell Activation Syndrome (MCAS) is a complex and often under-recognised condition where the body’s mast cells release excessive amounts of chemical mediators, leading to a wide range of allergic-type symptoms. These may include hives, gastrointestinal issues, flushing, fatigue, and even anaphylaxis in some cases.

At Ready Health in Standish, we understand how challenging it can be to get a timely diagnosis and access effective treatment for MCAS—especially when local NHS services may not always have pathways or access to certain medications. That’s why we’re proud to offer private GP services, access to specialist support, and a reliable route to diagnosis and management of MCAS.

Diagnosis of Mast Cell Activation Syndrome

Diagnosing MCAS can be a complex process as symptoms vary widely between individuals and often overlap with other conditions such as histamine intolerance or allergies. At Ready Health, we work closely with our private GPs and can arrange appropriate investigations, which may include:

Tryptase levels
24-hour urinary histamine or prostaglandin metabolites
Detailed symptom assessment and medical history

We ensure a personalised approach to every patient, offering the support and guidance needed throughout the diagnostic journey.

Treatment Options for MCAS

Managing MCAS typically involves a combination of trigger avoidance and medication to stabilise mast cells or block their effects. At Ready Health, we offer access to a range of treatments, including:

1. Sodium Cromoglicate (Nalcrom Capsules)

This mast cell stabiliser is particularly effective for gastrointestinal symptoms and is commonly prescribed as part of MCAS treatment. However, Nalcrom (Sodium Cromoglicate) may not be readily available on the NHS in all areas due to prescribing restrictions or supply issues.

✅ We can source and supply Nalcrom capsules privately. If you’re having trouble obtaining this vital medication, contact us and we’ll help.

2. Antihistamines

Both H1-antihistamines (such as cetirizine, loratadine, or fexofenadine) and H2-antihistamines (like ranitidine or famotidine) are commonly used to block histamine and reduce symptoms like itching, flushing, and gastrointestinal upset. These are often taken regularly in MCAS, not just during acute reactions.

3. Leukotriene Receptor Antagonists

Medications such as montelukast may be used to reduce inflammation related to mast cell mediator release.

4. Adrenaline Auto-Injectors (EpiPen)

Anyone diagnosed with MCAS should always carry an adrenaline auto-injector (e.g. EpiPen, Jext, Emerade) due to the risk of sudden severe reactions, including anaphylaxis. We can prescribe and provide guidance on safe use of auto-injectors, and ensure you are prepared in case of emergency.

Our Private GP Service – Supporting Your Journey

Our private GP at Ready Health offers:

Swift access to appointments
Personalised care plans tailored to MCAS
Ongoing review and support
Private prescriptions for medications like Sodium Cromoglicate/Nalcrom and antihistamines
Referral to allergy or immunology specialists if needed

We understand how frustrating it can be to navigate the healthcare system when dealing with a rare or misunderstood condition like MCAS. We're here to bridge the gap and ensure you receive the care and medication you need.

Struggling to Get the Right Medication? Let Us Help

If you or a loved one is living with Mast Cell Activation Syndrome and facing difficulties getting the necessary treatment—especially accessing Nalcrom (Sodium Cromoglicate Capsules)—contact Ready Health, Standish today. We can help guide you through the diagnosis process, support your treatment, and ensure you have reliable access to vital medications.

📞 Call us or 📧 email the clinic today to book a consultation with our private GP or Clinical Pharmacists.

Let us help you take control of your health with the right support and treatment options.