Mast Cell Activation Syndrome (MCAS) is a complex condition caused by excessive mast cell mediator release, leading to symptoms such as hives, gastrointestinal issues, flushing, fatigue, and sometimes anaphylaxis.

At Ready Health in Standish, our GP appointments are designed to listen, assess, and act. We take the time to understand your symptoms and, where MCAS is suspected, provide referral to one of only three UK specialists able to investigate and diagnose the condition.

With NHS pathways often limited, our private GP service offers a timely, reliable route to diagnosis and management of MCAS.

Following a confirmed diagnosis, we can also provide ongoing care, support, and access to medications to help manage the condition long term.

Diagnosis of Mast Cell Activation Syndrome

Diagnosing MCAS can be a complex process as symptoms vary widely between individuals and often overlap with other conditions such as histamine intolerance or allergies. At Ready Health, we work closely with our UK specialists partnerships and can arrange appropriate investigations, which may include:

Tryptase levels
24-hour urinary histamine or prostaglandin metabolites
Detailed symptom assessment and medical history

We provide ongoing care and support, taking the time to listen and ensuring a personalised approach for every patient throughout their diagnostic and treatment journey.

Treatment Options for MCAS

Managing MCAS typically involves a combination of trigger avoidance and medication to stabilise mast cells or block their effects. At Ready Health, we offer access to a range of treatments, including:

1. Sodium Cromoglicate (Nalcrom Capsules)

This mast cell stabiliser is particularly effective for gastrointestinal symptoms and is commonly prescribed as part of MCAS treatment. However, Nalcrom (Sodium Cromoglicate) may not be readily available on the NHS in all areas due to prescribing restrictions or supply issues.

✅ We can source and supply Nalcrom capsules privately. If you’re having trouble obtaining this vital medication, contact us and we’ll help.

2. Antihistamines

Both H1-antihistamines (such as cetirizine, loratadine, or fexofenadine) and H2-antihistamines (like ranitidine or famotidine) are commonly used to block histamine and reduce symptoms like itching, flushing, and gastrointestinal upset. These are often taken regularly in MCAS, not just during acute reactions.

3. Leukotriene Receptor Antagonists

Medications such as montelukast may be used to reduce inflammation related to mast cell mediator release.

4. Adrenaline Auto-Injectors (EpiPen)

Anyone diagnosed with MCAS should always carry an adrenaline auto-injector (e.g. EpiPen, Jext, Emerade) due to the risk of sudden severe reactions, including anaphylaxis. We can prescribe and provide guidance on safe use of auto-injectors, and ensure you are prepared in case of emergency.

Our Private GP Service – Supporting Your Journey

Our private GP at Ready Health offers:

Swift access to appointments
Referrals and bespoke care plans tailored to MCAS
Ongoing review and support
Private prescriptions for medications like Sodium Cromoglicate/Nalcrom and antihistamines
Referral to allergy or immunology specialists if needed

We understand how frustrating it can be to navigate the healthcare system when dealing with a rare or misunderstood condition like MCAS. We're here to bridge the gap and ensure you receive the care and medication you need.

You can book a standard GP appointment for ongoing clinical reviews and personalised care at Ready Health.

Struggling to Get the Right Medication? Let Us Help

If you or a loved one is living with Mast Cell Activation Syndrome and facing difficulties getting the necessary treatment—especially accessing Nalcrom (Sodium Cromoglicate Capsules)—contact Ready Health, Standish today. We can help guide you through the diagnosis process, support your treatment, and ensure you have reliable access to vital medications.

📞 Call us or 📧 email the clinic today to book a consultation with our private GP or Clinical Pharmacists.

Let us help you take control of your health with the right support and treatment options.