Switching from Mounjaro to Wegovy: What You Need to Know

With the recent price rises and supply changes, many patients are asking about switching from Mounjaro (tirzepatide) to Wegovy (semaglutide). Both are powerful weight loss injections, but they’re not the same — so making the switch safely matters.

Here’s everything you need to know.

Why Are People Switching?

There are a few common reasons patients are moving from Mounjaro to Wegovy:

• Cost pressures – Mounjaro prices have risen sharply, leaving some patients looking for more affordable options.

• Stock issues – limited global supply means patients may struggle to source their regular pens.

• Eligibility rules – while Mounjaro is not yet available on the NHS, some patients may qualify for Wegovy under NHS weight management programmes.

• Side effects – occasionally, people tolerate one injection better than the other.

Mounjaro vs Wegovy: Key Differences

Although both help with weight loss, they work slightly differently:

• Mounjaro (tirzepatide) – targets two hormones (GLP-1 and GIP) and is considered the more potent of the two.

• Wegovy (semaglutide) – targets GLP-1 only, but still highly effective for appetite control and weight reduction.

• Dosing – Mounjaro pens are available in multiple weekly doses up to 15mg. Wegovy starts at 0.25mg weekly and increases gradually up to a maximum of 2.4mg.

How to Switch Safely

Switching isn’t as simple as picking up where you left off — the two medications have different dosing systems.

• Washout period – allow one full week after your last Mounjaro injection before starting Wegovy. (See our guide: Washout Periods Explained)

• Start low, go slow – even if you were on a higher Mounjaro dose, you’ll usually begin Wegovy at 0.25mg weekly and gradually titrate up. This helps reduce side effects.

• Monitoring – your prescriber will review your progress, side effects, and appetite changes to adjust your plan.

FAQs We Hear at Ready Health

💬 Will I lose the same amount of weight?
Results vary. Some patients lose at a similar rate, while others notice a slower pace on Wegovy compared to Mounjaro.

💬 Will I get side effects again?
Possibly. Starting Wegovy at a lower dose can mean side effects like nausea return temporarily — but they usually settle.

💬 What if my BMI is now under 30?
This can affect eligibility. NHS rules only cover Wegovy for people with a BMI of 30+ (or 27+ with certain conditions). However, private clinics like Ready Health can still support you.

How Ready Health Can Help

At our clinic in Standish, we:

• Assess your suitability for Wegovy based on your health and history.

• Create a tailored switching plan so you move across safely.

• Provide ongoing support with dose reviews, side effect management, and motivational check-ins.

Final Thoughts

Switching from Mounjaro to Wegovy is increasingly common, and with the right guidance, it can be smooth and effective. The key is not to self-switch — always work with a prescriber to avoid gaps, side effects, or dose errors.

👉 Book a consultation with Ready Health’s Weight Management Team to get expert support for your switch.